The majority of the devices developed in the field of organic bioelectronics rely on efficient and balanced mixed ionic and electronic conduction in the organic material. For instance, the performance of an organic electrochemical transistor (OECT) depends on how easily the electronic charge carriers move along the film, how keen the material is to uptake (de)dopant ions, and eventually how efficiently these ions affect the output current.
Detecting disease biomarkers or analytes and quantifying minute changes in their concentrations in bodily fluids, in the living tissue or at single cell level is one of the biggest endeavors of the biomedical engineers. We tackle this challenge by integrating biofunctionalized mixed conductors in customized electronic devices so that they have high sensitivity, specificity and speed.
Conducting polymers can be processed to exhibit a variety of form factors such as porous structures or fibrous films. Once these architectures are integrated with cell culture, a 3D living bioelectronic device can be developed. Modifying the scaffolds, our work aims to design 3D sensing/actuating platforms that have an intimate interface with cells.